710 Military Cutoff Rd. Suite 320, Wilmington, NC 28405

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Defyne and Refyne in Wilmington, NC

Not amused by your laugh lines? Feeling played by your marionette lines?

Restylane® Defyne and Refyne fillers can restore lost volume and treat moderate to severe wrinkles and folds in the nose and mouth area. Rosalyn George, M.D., leads a team of physicians and aesthetic professionals fully dedicated to providing natural, substantial correction with minimal downtime.

Restylane® Defyne and Refyne fillers in Wilmington

What are Restylane® Defyne and Refyne Fillers?

Restylane® Defyne and Refyne are clear gel injectable fillers that do as their name suggests: define and refine your skin.

  • Restylane® Defyne is used to treat deep wrinkles and folds or replace lost volume under the skin. It provides definition for areas around your mouth and nose. Defyne can make even your most dramatic expressions look soft and natural, not puffy and stiff.
  • Restylane® Refyne provides a mid-level lifting effect and treats moderate wrinkles and lines. Where Defyne creates new definition, Refyne offers refinement to similar treatment areas. Refyne is perfect for subtly de-aging your face in a way that looks completely natural.

Both the Defyne filler and the Refyne filler use hyaluronic acid (HA), a naturally-occurring substance in our bodies that we simply lose over time. Each of these injectables provides specially-formulated hyaluronic acid compounds to specific treatment areas for natural, youthful results. These are great, non-surgical options with minimal downtime and results lasting up to 12 months.

Why Receive Restylane® Defyne and Refyne at Wilmington Dermatology Center?

Restylane® Defyne and Refyne are both subtle and powerful treatment options, but the skill and techniques of the provider — how much filler to use, where to inject it, and more — will impact how significant and natural your results look. Dr. Rosalyn George’s team at Wilmington Dermatology Center is recognized as the top Coastal North Carolina practice by Restylane® creator Galderma, and Dr. George herself is an official trainer for Galderma products.

Why Receive Restylane® Defyne and Refyne at Wilmington Dermatology Center?

Restylane® Defyne and Refyne are both subtle and powerful treatment options, but the skill and techniques of the provider — how much filler to use, where to inject it, and more — will impact how significant and natural your results look. Dr. Rosalyn George’s team at Wilmington Dermatology Center is recognized as the top Coastal North Carolina practice by Restylane® creator Galderma, and Dr. George herself is an official trainer for Galderma products.

How Do Restylane® Defyne and Refyne Fillers Work?

As with all our injectable filler treatments, we begin with a complimentary consultation. We’ll discuss your aesthetic goals and evaluate your skin to determine which treatment best fits your case.

Prior to Treatment

On the day of your appointment, we apply a topical, lidocaine-based numbing cream to the treatment areas. After waiting 10 to 15 minutes for it to take effect, we’ll thoroughly cleanse the target areas.

During Treatment

We’ll inject carefully-considered amounts of Defyne filler or Refyne filler in the areas that will provide the most significant and natural-looking results. There is lidocaine in the gel to further help with the minor pinch and pressure felt during injection. Depending on your goals and the target areas, this may require multiple injections, and this process typically takes 30 to 40 minutes.

After Treatment & Results

You’ll be given a cooling agent to apply to the treated areas after the procedure. You may experience swelling and bruising that shouldn’t last more than a week. Results will be evident immediately after the procedure, but full correction will take a week. Results can last up to 12 months.

Love The Skin You’re In

Susan Stone
Susan Stone
2024-02-14
The office is run very well by professional but friendly staff. Savanna made me feel comfortable during my visit.
Kenneth Rademacher
Kenneth Rademacher
2024-02-13
Very professional, thorough, and kept me informed and answered all my concerns
Cecilia Difini
Cecilia Difini
2024-02-09
I had my eyebrows done by Nicole and I couldn’t be happier, not only do they look great but she us awesome !
Marsha Freedman
Marsha Freedman
2024-02-09
Our appointment was on time. The doctor was wonderful and so was the staff. I'll definitely go back as needed
Glenn Patterson
Glenn Patterson
2024-02-09
I highly recommend Karin. Her examinations are very thorough and if there's something wrong she will find it.
K BBV Welsh
K BBV Welsh
2024-02-08
Great service and very nice staff. Dr George is great and very professional.

Love The Skin You’re In

Susan Stone
Susan Stone
2024-02-14
The office is run very well by professional but friendly staff. Savanna made me feel comfortable during my visit.
Kenneth Rademacher
Kenneth Rademacher
2024-02-13
Very professional, thorough, and kept me informed and answered all my concerns
Cecilia Difini
Cecilia Difini
2024-02-09
I had my eyebrows done by Nicole and I couldn’t be happier, not only do they look great but she us awesome !
Marsha Freedman
Marsha Freedman
2024-02-09
Our appointment was on time. The doctor was wonderful and so was the staff. I'll definitely go back as needed
Glenn Patterson
Glenn Patterson
2024-02-09
I highly recommend Karin. Her examinations are very thorough and if there's something wrong she will find it.
K BBV Welsh
K BBV Welsh
2024-02-08
Great service and very nice staff. Dr George is great and very professional.
History of Restylane® Defyne and Refyne

What is the History of Restylane® Defyne and Refyne?

Restylane® Defyne and Refyne were developed using XpresHAn technology, which allows for a high degree of customization in the flexibility, support, and other characteristics each filler can provide. They were first approved for use in 2010 and have helped millions worldwide.

Both Defyne and Refyne were developed by Galderma and are eligible for credit towards their Aspire Galderma Rewards program. Sign up for your free membership at your first visit for an instant reward!

Am I a Candidate for Restylane® Defyne and Refyne?

Restylane® Defyne and Refyne are perfect for men and women who want to increase volume and decrease wrinkles and signs of aging around the nose and mouth with a nonsurgical procedure. We can help you choose which of these or other fillers will most benefit your skin during a free consultation.

You should let us know if you are allergic to any ingredients in Restylane® Defyne and Refyne including lidocaine, have reacted poorly to other HA products, have an infection in a planned treatment area, are pregnant, plan to become pregnant, or are breastfeeding.

Restylane® Defyne and Refyne Frequently Asked Questions

How long do Restylane® Refyne or Restylane® Defyne last?

Restylane® Refyne and Restylane® Defyne have been proven to last up to 12 months.

When will I see results?

Restylane® Refyne and Defyne results are evident immediately, and you can expect full correction within a week.

Is one of these options better than the other, or similar products?

There are many fillers that are all perfectly effective, but some are better for certain cosmetic goals than others. Defyne filler is mainly used to add volume and reduce deep wrinkles around the nose and mouth, while Refyne filler treats moderate wrinkles, most often between the mouth and nose.

Can I get Restylane® Refyne or Restylane® Defyne the day before a big event?

Both Refyne and Defyne treatment have potential for downtime. Not everyone bruises, but most will experience swelling at a minimum. These side effects should disappear within a week.

Does the Restylane® Refyne or Restylane® Defyne procedure hurt?

Between numbing cream and anesthetic within the filler, most patients experience a pinch with some pressure. Some spots can be more sensitive than others, but most patients tolerate it without issue.

How Do Restylane® Refyne or Restylane® Defyne filler work?

The body contains hyaluronic acid (HA) that helps support skin, but this fades naturally over time. Restylane® Defyne and Refyne build up the lost natural HA in the skin. They’re tailored with XpresHAn technology to provide varying amounts of treatment for natural results in all areas of the face.

Does it really matter who does my Restylane® Refyne or Restylane® Defyne?

Restylane® Defyne and Refyne are incredibly useful tools, but still require someone who knows how to use them for results that are both significant and completely natural looking. We recommend you use a highly trained-medical provider who understands facial anatomy at a deep level, like our own Dr. Rosalyn George, to perform the procedure to prevent complications and provide exceptional results.

Can I get Restylane® Refyne or Restylane® Defyne done the same day as other injectable procedures?

Yes, you can receive Restylane® Defyne and Refyne the same day as other fillers such as BOTOX®, Dysport®, and VOLLURE™.

We do ask that you let us know if you’re getting laser treatment, as fillers should be done afterwards.

What happens if I need more correction or I didn’t achieve the results I’d anticipated?

It’s important to everyone at Wilmington Dermatology Center that our patients are as satisfied with their treatment as possible. We offer a two-week follow-up for Restylane® Defyne and Refyne, where we can evaluate your results and adjust treatment as necessary.

How Much Do Restylane® Defyne and Refyne Cost?

The cost of treatment with Restylane® Defyne and Refyne depends mainly on how many syringes are necessary to give you the results you’re looking for. We’ll discuss your optimal treatment plan and potential cost during your free consultation.

Patient Documents

Please download and view the Restylane® Refyne and Defyne pre-visit instructions ahead of your visit.

Please download and view the Restylane® Refyne and Defyne pre-visit instructions ahead of your visit.